角膜移植术后会出现排斥反应吗?

楼主:youcong 时间:2021-03-01 16:34:06 点击:3 回复:0
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  一般全层角膜移植术后均可出现排斥反应,只是反应的程度轻重不同,排斥反应的轻重主要与供体角膜移植片的大小,移植片的健康情况,内皮细胞的丢失情况,移植片的处理及保存有关;与移植床有无新生血管,虹膜、睫状体等的炎症反应,虹膜、睫状体等有无病变有关,与手术状况、手术方式、手术次数、时间及部位,手术者的技术水平有关;更主要是与组织相容抗原性有关,供体与受体的组织相容抗原越接近排斥反应越小。开始时发生的排斥反应在术后1周;大约占10%;轻者持续2~3周用激素、免疫抑制剂后可消退;远期的排斥反应多发生术后的3个月到半年,所以角膜移植术后用药至少半年以上。

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